Ex: C0006933 C0007102 C0007203 C3175196    or

CUI: C1135132   ixabepilone 
An enteric-coated formulation of ixabepilone, a semisynthetic analogue of epothilone B and a non-taxane tubulin inhibitor, with antineoplastic activity. Ixabepilone binds to and stabilizes tubulin molecules, thereby interfering with the dynamics of microtubule assembly/disassembly. This results in cell cycle arrest at the G2-M phase and leads to apoptosis within fast growing tumor cells. This agent demonstrates antineoplastic activity against taxane-resistant cell lines. Compared to intravenously administered ixabepilone, the oral formulation provides a more manageable way to administer this agent.

rdfs:seeAlso — C0042686 C1522570 C0001558 C0013153 C0030547 C0085104 C0175795 C0678823 C1136199 C1513727 C1518896 C0524527 C0220806 C1706082 C1550600 C1261512 C1449772 C1552125 C0596922

skos:closeMatch —

skos:exactMatch — C0879430 C1135132 C1967552 C0297960 C0962559 C1135132 C1136012

UMLS Concepts to DBPedia Link Discovery Browser

Enter an UMLS concept-unique-identifier (CUI) or DBPEDIA resource uri to show its rdfs:seeAlso, skos:closeMatch, and skos:exactMatch mapped relations to DBpedia. Alternatively, you can click on a CUI from the sample list to the right to compare our mapping to Wikidata.