Ex: C0006933 C0007102 C0007203 C3175196    or

CUI: C2827241   lomitapide 
A small molecule inhibitor of microsomal triglyceride transfer protein (MTP), an enzyme located in the lumen of the endoplasmic reticulum responsible for absorbing dietary lipids and transferring triglycerides onto apolipoprotein B (apo-B) in the assembly of very-low-density lipoprotein. Inhibition of MTP by lomitapide blocks transfer of lipid to apo-B, and as a result emerging apo-B is destroyed and lipoprotein secretion is inhibited.

rdfs:seeAlso — C0005580 C0058372 C2754083 C2979948 C0596258 C0596259 C0682936 C0002508 C0596072 C0597565 C0682958 C1879694 C0243077 C3463820 C0014432 C0678613 C1333403 C1524081 C1999216

skos:closeMatch —

skos:exactMatch — C1176233 C2606889 C2827241 C3530501

UMLS Concepts to DBPedia Link Discovery Browser

Enter an UMLS concept-unique-identifier (CUI) or DBPEDIA resource uri to show its rdfs:seeAlso, skos:closeMatch, and skos:exactMatch mapped relations to DBpedia. Alternatively, you can click on a CUI from the sample list to the right to compare our mapping to Wikidata.