CUI ⟾ or DBPEDIA ⟾
Ex: C0006933 C0007102 C0007203 C3175196    or    http://dbpedia.org/resource/Nosebleed    http://dbpedia.org/resource/Leg

CUI: C3853822   palbociclib 
An orally available cyclin-dependent kinase (CDK) inhibitor with potential antineoplastic activity. Palbociclib selectively inhibits cyclin-dependent kinase 4 (CDK4) and 6 (CDK6), thereby inhibiting retinoblastoma (Rb) protein phosphorylation early in the G1 phase leading to cell cycle arrest. This suppresses DNA replication and decreases tumor cell proliferation. CDK4 and 6 are serine/threonine kinases that are upregulated in many tumor cell types and play a key role in the regulation of cell cycle progression.

rdfs:seeAlso —
http://dbpedia.org/resource/Acetyl C2985512
http://dbpedia.org/resource/Piperazine C0031957 C0031958 C1145666 C1617066 C2698816 C2713578
http://dbpedia.org/resource/Mouth C0226896 C0442119 C0457008
http://dbpedia.org/resource/Methyl_group C0596922

skos:closeMatch —

skos:exactMatch —
http://dbpedia.org/resource/Palbociclib C1568660 C3853822 C3883373


UMLS Concepts to DBPedia Link Discovery Browser


Enter an UMLS concept-unique-identifier (CUI) or DBPEDIA resource uri to show its rdfs:seeAlso, skos:closeMatch, and skos:exactMatch mapped relations to DBpedia. Alternatively, you can click on a CUI from the sample list to the right to compare our mapping to Wikidata.